Health Condition 1: K746- Other and unspecified cirrhosis ofliver
Conditions
Interventions
Intervention1: Inj CEFOTAXIME: 1 GM I.V. TDS for 3 days
Control Intervention1: CEFOTAXIME: ONE ARM WIIL BE GIVEN CEFOTAXIME
Control Intervention2: MEROPENEM: ONE ARM WILL BE GIVEN MEROPENEM
Control In
Sponsors
JLN MEDICAL COLLEGE AJMER
Eligibility
Inclusion criteria
Inclusion criteria: 1.Liver cirrhosis patients with ascitic fluid PMN cell count greater than 250/mm3 (treatment naive). 2.Age equal or greater than 18 years. 3.Patient who give informed consent.
Exclusion criteria
Exclusion criteria: 1.History of abdominal surgery within 4 weeks 2.Secondary peritonitis 3.Tuberculous peritonitis 4.Malignant ascites 5.Patients on immunosuppressants 6.AIDS patients. 7.Creatinine clearance less than 50 mL/min.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Follow-up paracentesis after 48 hours of initiation of empirical antibiotic treatment showing reduction in neutrophil count of at least 25% or Decrease of peritoneal fluid PMN count to less than 250 cells/µ and negative previously positive ascitic fluid culture.Timepoint: 2 days | — |
Secondary
| Measure | Time frame |
|---|---|
| role of serum procalcitonin as a marker of SBPTimepoint: At baseline & after 2 days | — |
Countries
India
Contacts
Public ContactRISHABH PARASHAR
JLN MEDICAL COLLEGE, AJMER
Outcome results
None listed