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Development of mathematical tool for predicting probable outcome in patients with severe bacterial infections in paediatric ICU

Development of prognostic model for paediatric patients with Gram-negative infections undergoing antibiotic therapy in paediatric ICU - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/08/073091
Enrollment
271
Registered
2024-08-29
Start date
Unknown
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B999- Unspecified infectious disease

Interventions

Intervention1: NIL: NIL

Sponsors

NIL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: The study includes patients admitted to Paediatric ICU with Gram-negative infections, aged between 28 days and 18 years, and patients with a creatinine clearance (ClCr) above 50mL/min and receiving antibiotics Inj. Ceftriaxone and Inj. Amikacin either alone or in combinations for over 48 hours

Exclusion criteria

Exclusion criteria: The patients undergoing treatment with extracorporeal membrane oxygenation (ECMO) or renal replacement therapy (RRT).

Design outcomes

Primary

MeasureTime frame
A prognostic model will be developed for predicting outcome of pediatric patients with Gram-negative infectionsTimepoint: 3 years—

Secondary

MeasureTime frame
Estimated serum antibiotic levels and antibiotic susceptibility profiles correlating with clinical outcomes, will help clinicians optimise antibiotic regimens for pediatric patients.Timepoint: 3 years—

Countries

India

Contacts

Public ContactDr VijayanarayanaK

Manipal College of Pharmaceutical Sciences

vijayanarayana.k@manipal.edu9448255124

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026