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A Comparative Analysis of Various Irrigants on Substance P Expression in Single-Visit Root Canal Treatment for Teeth with Irreversible Pulpitis

Comparative Evaluation Of Different Irrigants On Substance P Expression For Single Visit Root Canal Treatment Of Teeth With Irreversible Pulpitis - A Double Blinded Study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/08/073074
Enrollment
84
Registered
2024-08-29
Start date
Unknown
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K040- Pulpitis

Interventions

Intervention1: Irrigant solution: 5ml of irrigant Administered intracanal for 1 minute after every preparation Control Intervention1: Irrigating Solution: 5.25% SODIUM HYPOCHLROITE, ketorolac trometh

Sponsors

Dr Lubn Hassan
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patient must be prsent with pain due to irreversible pulpitis from carious teeth requiring root canal treatment.

Exclusion criteria

Exclusion criteria: No periapical bone changes on the pre-operative radiograph Any variation in the root canal anatomy and patient not willing to sign the informed consent.

Design outcomes

Primary

MeasureTime frame
1-post-operative pain Timepoint: 1-after 24 hours of initiation of the treatment—

Secondary

MeasureTime frame
substance P expressionTimepoint: after 2 months of treatment initiation—

Countries

India

Contacts

Public ContactDr Sonali Taneja

I.T.S Centre For Dental Studies And Research,

sonalitaneja@its.edu.in9891688100

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026