Health Condition 1: Z428- Encounter for other plastic and reconstructive surgery following medical procedure or healed injury
Conditions
Interventions
Intervention1: Nitroglycerine 400ug: Agent : nitroglycerine 400ug 1 puff + lignocaine 15% 2 puff 1 minute before laryngoscopy. Route sublingual
Control Intervention1: Lignocaine (15%): Comparator: lig
Sponsors
King Georges Medical University
Ajay Kumar Chaudhary
Eligibility
Inclusion criteria
Inclusion criteria: Patients who were classified as ASA grade I/II, had ages ranging between 18 to 60 years, were scheduled for elective surgeries under general anesthesia with endotracheal intubation, and provided written informed consent will be included in the study.
Exclusion criteria
Exclusion criteria: Patients who exhibited allergy to the study drug, anticipated difficult airways, required emergency surgical procedures, possessed a history of laryngeal or tracheal surgery or any related pathology, had pre-existing cardiac disease, hypertension, or chronic obstructive pulmonary disease (COPD), or refused to provide consent will be excluded from participation in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To measure and compare the effect of Nitroglycerine 400ug with lignocaine (15%) 2 puff and Lignocaine (15%) 2 puff alone on the hemodynamic responses to laryngoscopy and endotracheal intubation.Timepoint: •At intervals of 1, 3, 5, 10, and 15 minutes after laryngoscopy and tracheal intubation, the vital parameters will be monitored and compared. | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the adverse effect of the Nitroglycerine 400ug with lignocaine (15%) 2 puff & Lignocaine (15%) 2 puff alone on the hemodynamic responses to laryngoscopy & endotracheal intubation.Timepoint: During & after laryngoscopy & tracheal intubation (Approximately 30 min) | — |
Countries
India
Contacts
Public ContactVasioullah Khan
King Georges Medical University
Outcome results
None listed