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comparative study between magnesium sulphate and clonidine on hemodynamic response and intubation during laproscopic surgery

Comparative study of intravenous injection of CLONIDINE and/or MAGNESIUM SULPHATE on hemodynamic response to tracheal intubation and pneumoperitoneum during laproscopic surgeries - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/08/072986
Enrollment
100
Registered
2024-08-27
Start date
Unknown
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Hemodynamic response to magnesium sulphate versus clonidine: GROUP M will recieve 30mg/ Kg of magnesium sulphate in 20 ml normal saline over 10 minutes GROUP C will recieve 1 microg/ Kg

Sponsors

Dr Ram Nandan Prasad Professor of Anaesthesiology
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA I AND II AND BMI between 20-35 and elective laproscopic cholecystectomy

Exclusion criteria

Exclusion criteria: patients not provinding consent Contraindication or allergy to any study drug patient with asthma, epilepsy , hemodynamic unsatble or deranged coagulation profile pregnant and lactating women patient with hypermagnesemia hypertension morbid obesity severe hepatic, renal, endocrine and cardiac dysfunction

Design outcomes

Primary

MeasureTime frame
to compare the mean arterial pressure at 5 minutes between two groupsTimepoint: to compare the mean arterial pressure at 5 minutes between two groups—

Secondary

MeasureTime frame
to compare the effect of clonidine & magnesium sulphate on post operative recovery such as time for extubation & time to verbal responseTimepoint: pain & sedation score assess in recovery room on arrival & after 30 minutes, 1 hour, 2hours, 3hours, 4 hours—

Countries

India

Contacts

Public ContactDr Ram Nandan Prasad

MM Institute of Medical Sciences and Research, MULLANA AMBALA

hersimran89mbbs@gmail.com6283155919

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026