Evaluating the effectiveness of ultrasound guided pain relief methods for knee replacement surgeries

To study the analgesic effectiveness of anterior femoral cutaneous nerve block in addition to proximal adductor canal block and local infiltration analgesia in patients undergoing unilateral primary total knee arthroplasty: A randomised controlled trial - nil

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/08/072985

Enrollment

Registered

2024-08-27

Start date

Unknown

Completion date

Unknown

Last updated

2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M171- Unilateral primary osteoarthritisof knee

Interventions

Intervention1: Anterior femoral cutaneous nerve block + Adductor canal block along with local infiltration analgesia: Patients will receive adductor canal block and Local infiltration analgesia: Patie

Eligibility

Inclusion criteria

Inclusion criteria: 1) ASA I+II+III 2) 18 TO 70 Years 3) Patients undergoing unilateral primary Total knee arthroplasty

Exclusion criteria

Exclusion criteria: 1.Patient refusal 2.Varus valgus deformity > 20 degree 3.Flexion deformity > 30 degree 4.BMI > 30 kg/sq.cm 5.Contraindication to neuraxial anaesthesia 6.Allergy to local anaesthetics, NSAIDS, Opioids 7.Chronic opioid use > 3 month duration 8.Previous knee surgery 9.Pregnant females at the time of recruitment 10.Progressive neurological deficit in femoral, obturator or sciatic nerve distribution. 11.Severe cardiac co-morbidities, hepatic or renal dysfunction, coagulopathy

Design outcomes

Primary

Measure	Time frame
Cumulative postoperative analgesic consumption in 36 hours as IV morphine equivalentsTimepoint: 36 hours	—

Secondary

Measure	Time frame
1.Numeric rating scale of pain (0 minimum-10 worst pain) at various intervals 2.NRS at movement after mobilization at various time intervals 3.Time of first rescue analgesic 4.Quality of Recovery (QoR -15) at 24 hr and 48 hr 5.Timed up and go (TUG) Test scores 6.Patient satisfaction 7.Length of hospital stay 8.Sleep quality (no of times awakening because of Pain) 9.Observe any adverse effect (following LIA, ACB and AFCB -vascular puncture, motor blockade or Local analgesic systemic toxicity).Timepoint: 1.0, 30 min, 1 hr,2 , 4 ,6 , 8, 12, 24 ,36 and 48 hours	—

Measure

Time frame

1.Numeric rating scale of pain (0 minimum-10 worst pain) at various intervals 2.NRS at movement after mobilization at various time intervals 3.Time of first rescue analgesic 4.Quality of Recovery (QoR -15) at 24 hr and 48 hr 5.Timed up and go (TUG) Test scores 6.Patient satisfaction 7.Length of hospital stay 8.Sleep quality (no of times awakening because of Pain) 9.Observe any adverse effect (following LIA, ACB and AFCB -vascular puncture, motor blockade or Local analgesic systemic toxicity).Timepoint: 1.0, 30 min, 1 hr,2 , 4 ,6 , 8, 12, 24 ,36 and 48 hours

—

Countries

India

Contacts

Public ContactSudhir Anand

AIIMS New Delhi

drdebeshbhoi@aiims.edu7042129428

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026