"Randomized Controlled Trial on Photobiomodulation with CO2 and Diode Lasers: Impact on Implant Stability, Post-Surgical Healing, and Inflammation in Dental Patients"

Comparative Evaluation Of The Implant Stability, Post-surgical Healing And Inflammation By Photobiomodulation Using CO2 Laser And Diode Laser: Randomized Controlled Trial. - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/08/072894

Enrollment

Registered

2024-08-22

Start date

Unknown

Completion date

Unknown

Last updated

2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: K089- Disorder of teeth and supporting structures, unspecified

Interventions

Intervention1: Patients receiving CO 2 laser photobiomodulation during implant surgery. : after explaining the study to the patients, an informed consent will be taken from the patient before the st

and the occlusal side, to stimulate mucosal tissue regeneration and anti-inflammatory effect. 3. The laser treatment will repeat 10 days later after suture removal. Intervention2: Patients receivin

and the occlusal side, to stimulate mucosal tissue regeneration and anti-inflammatory effect. 3. laser treatment will repeat 10 days later after suture removal. Control Intervention1: Implants will b

Eligibility

Inclusion criteria

Inclusion criteria: 1) Patients above 18 years of age. 2) Patients who opt for dental implant surgery for a missing tooth. 3) Thin biotype 4) Patient with healthy systemic condition. 5) Adequate oral hygiene levels.

Exclusion criteria

Exclusion criteria: 1. Patients with systemic diseases that contraindicate the surgery, immune-compromised patients. 2. Patients with implant sites that presented complications. 3. Pregnant or lactating females. 4. Patients not willing to participate in the study.

Design outcomes

Primary

Measure	Time frame
The primary outcomes measured will be implant stability, post-surgical healing, and inflammation. Implant stability will be assessed using resonance frequency analysis. Healing will be evaluated through clinical assessments using the Landry healing index, and inflammation will be measured by clinical signs and potentially biochemical markers in peri-implant crevicular fluid. This methodological structure allows the study to rigorously test the efficacy of two different types of lasers in improving the clinical outcomes of dental implants, providing clear insights into which modality might be more effective or if photobiomodulation offers significant benefits over traditional implant procedures without such interventions. Timepoint: T0 at baseline period T1 at 10 days T2 at 4 weeks T3 at 3 months	—

Measure

Time frame

The primary outcomes measured will be implant stability, post-surgical healing, and inflammation. Implant stability will be assessed using resonance frequency analysis. Healing will be evaluated through clinical assessments using the Landry healing index, and inflammation will be measured by clinical signs and potentially biochemical markers in peri-implant crevicular fluid. This methodological structure allows the study to rigorously test the efficacy of two different types of lasers in improving the clinical outcomes of dental implants, providing clear insights into which modality might be more effective or if photobiomodulation offers significant benefits over traditional implant procedures without such interventions. Timepoint: T0 at baseline period T1 at 10 days T2 at 4 weeks T3 at 3 months

—

Secondary

Measure	Time frame
This methodological structure allows the study to rigorously test the efficacy of two different types of lasers in improving the clinical outcomes of dental implants, providing clear insights into which modality might be more effective or if photobiomodulation offers significant benefits over traditional implant procedures without such interventions. Timepoint: T0 at baseline period T1 at 10 days T2 at 4 weeks T3 at 3 months	—

Measure

Time frame

This methodological structure allows the study to rigorously test the efficacy of two different types of lasers in improving the clinical outcomes of dental implants, providing clear insights into which modality might be more effective or if photobiomodulation offers significant benefits over traditional implant procedures without such interventions. Timepoint: T0 at baseline period T1 at 10 days T2 at 4 weeks T3 at 3 months

—

Countries

India

Contacts

Public ContactDr Vaibhav Karemore

Government dental college and hospital

hageyakang97@gmail.com08413060310

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026