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Comparison of Nanohydroxyapatite powder extract dissolved in collagen sponge Platelet derived growth factor and MTA used in caries extending to pulp cases - A Randomized control trial

Comparative Evaluation Of Nanohydroxyapatite crystals Infused In Inert Collagen Sponge Platelet Derived Growth Factor (PDGF-BB) And Mineral Trioxide aggregate (MTA) as Direct Pulp Capping Agents- A Randomised Control Trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/08/072890
Enrollment
36
Registered
2024-08-22
Start date
Unknown
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K029- Dental caries, unspecified

Interventions

Intervention1: Nanohydroxyapatite crystals infused in collagen sponge: Nanohydroxyapatite powder and Collagen sponge (6 months) Intervention2: Platelet derived growth factor gel and Type I collagen pa

Sponsors

Dr Vidulasri N
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: The inclusion criteria included healthy male and female individuals from 18-45 years of age Asymp­tomatic maxillary and mandibular molars and premolars with microscopic carious pulpal exposure of (0.5 -1 mm), not tender to percussion; Normal response to cold and electric pulp testing; Ra­diographic evidence of deep caries approximating the pulp chamber with no evidence of thickening/ widening of peri­odontal ligament, absence of furcation radiolucencies and periapical pathology

Exclusion criteria

Exclusion criteria: The exclusion criteria are symptomatic teeth (history of spontaneous pain), Radiographic evidence of periapical changes or pathology, negative response to pulp sensibil­ity testing and exaggerated response, History of systemic diseases, tooth not conducive for rubber dam isolation, History of previous restoration in the tooth under consideration for pulp capping, periodon­tally compromised teeth, Pregnant and lactating women , patients with unsat­isfactory oral hygiene maintenance

Design outcomes

Primary

MeasureTime frame
Volume of dentin bridge formed using Nanohydroxyapatite powder,platelet derived growth factor, MTATimepoint: 3 months and 6 months

Secondary

MeasureTime frame
Difference between these direct pulp capping agents and which agent provides better results in volume of dentin bridge formationTimepoint: 3 months and 6 months

Countries

India

Contacts

Public ContactDr Vidulasri N

Karpaga Vinayaga Institute Of Dental Sciences

selvendranmds@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026