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Understanding the utility of MRI sequences in the evaluation of brain Stroke

Quantification of Ischemic Lesion using Intravoxel Incoherent Motion and prediction of Motor Outcome with Diffusion Kurtosis Imaging in Acute Stroke - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/08/072873
Enrollment
176
Registered
2024-08-22
Start date
Unknown
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I63- Cerebral infarction

Interventions

Intervention1: NIL: NIL Control Intervention1: NIL: NIL

Sponsors

Manipal College of Health Professions
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Phase 1 Patients with first ever stroke and early stroke symptoms like Upper or lower limb weakness slurring of speech or blurring of vision Time between the onset of symptoms and MRI scan less than 24 hours Phase 2 1 Unilateral first-ever stroke occurred due to middle cerebral artery occlusion

Exclusion criteria

Exclusion criteria: Phase 1 Presence of any hemorrhage traumatic or space-occupying lesion in the brain Ischemic lesions smaller than 0.5 cm Those having a non-penumbra core on imaging Phase 2 Multiple Focal infarcts Patients with a history of motor disability due to other underlying causes

Design outcomes

Primary

MeasureTime frame
phase 1 IVIM parameters and NIHSS score Phase 2 DKI parameters and Fugl-Meyer assessment score at baseline, 1 and 3 months after strokeTimepoint: baseline, 1 and 3 months after stroke

Secondary

MeasureTime frame
NATimepoint: NIL

Countries

India

Contacts

Public ContactDr Priyanka

Manipal College of Health Professions

priyanka.rao@manipal.edu9739314908

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026