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A study to assess the effect of lignocaine in no sedation bronchoscopy.

Effect of nebulized lignocaine in no sedation bronchoscopy: A randomised control trial in sub Himalayan population - Nil

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/08/072863
Enrollment
100
Registered
2024-08-21
Start date
Unknown
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J99- Respiratory disorders in diseasesclassified elsewhere

Interventions

Intervention1: Normal Saline 0.9%: Nebulization with 0.9% normal saline (4CC) in flexible bronchoscopy over 10 min. Control Intervention1: Lignocaine 2%: Nebulization with 2% Lignocaine solution (4CC)

Sponsors

Dr Rajendra Prasad Govt Medical College Tanda
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Adult patient more than 18 years or older, who are planned for flexible bronchoscopy. 2.Bronchoscopy performed for the first time. 3.Hemodynamically stable (Systolic BP more than 100 and less than 180 mm of Hg.)

Exclusion criteria

Exclusion criteria: 1. Patient not willing to give written informed consent. 2.Pregnant female. 3. Hypoxemia (oxygen saturation [by pulse oximetry] less than 90% at room air. 4.Bronchoscopy performed through endotracheal, tracheostomy tube or oral route. 5.subjects planned for administrations of upfront sedation. 6.Subjects with documented hypersensitivity to lignocaine. 7.Had a baseline systolic pressure of more than 180 or less than 100 mm of Hg, baseline heart rate of more than 100 beats per minute of less than 50 beats per minute or any other arrythmia.

Design outcomes

Primary

MeasureTime frame
Operator-rated cough scores on visual analogue scale between the group.Timepoint: During Procedure and after 2 hours of procedure

Secondary

MeasureTime frame
1. Cumulative lignocaine dose. 2. Patient receiving lignocaine more than 8.2 mg/kg. 3. Patient willingness to return for repeat procedure. 4. Complications if any. 5. Time to cross vocal cord.Timepoint: During Procedure and after 2 hours of procedure

Countries

India

Contacts

Public ContactDr Devendra Singh Dadhwal

Dr Rajendra Prasad Government Medical College Tanda HP

atalsood7@gmail.com9418063191

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026