Health Condition 1: O- Medical and Surgical Health Condition 2: M958- Other specified acquired deformities of musculoskeletal system
Conditions
Interventions
Intervention1: 0.75 microgram per kilogram dexmedetomidine as a premedication to 0.5% intrathecal levobupivacaine: 0.75 microgram per kilogram dexmedetomidine will be administered intravenously over
Sponsors
velammal medical college and hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1.All adult patients with ASA physical status I or II 2.either sex 3.18–60 years age 4.48–90 kg weight, 151–180 cm height and body mass index (BMI) between 20 and 35 kg/m2
Exclusion criteria
Exclusion criteria: We excluded the patients 1.with known hypersensitivity to LA, 2.infection at the injection site 3.history of bleeding disorders or on anticoagulants, 4.pregnancy, anatomical abnormality, and any comorbid condition such as preexisting peripheral neuropathy or neurological deficit, cerebrovascular accidents, endocrine, severe hepatic and renal dysfunction, chronic obstructive pulmonary disease, diabetes, sepsis, heart blocks, or dysrhythmias. Patients on tranquilizers, hypnotics, sedatives, and other psychotropic drugs and drug addicts to opium or alcohol.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| onset of sensory block Time taken to achieve highest level onset of motor blockade Recovery of sensory block Recovery of motor block Duration of analgesia Timepoint: Results will be assessed between 4 and 8 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart rate Mean arterial pressureTimepoint: secondary parameters were noted before premedication,2 mins after premedication,60 seconds after dural puncture,15mins,20 mins,25 mins,30 mins,40 mins,50 mins,60 mins,70 mins,80 mins,90 mins,120 mins, and 180 mins after dural puncture | — |
Countries
India
Contacts
Public ContactDR.T.NIRMALA DEVI
Velammal Hospital and Medical College
Outcome results
None listed