Health Condition 1: K056- Periodontal disease, unspecified
Conditions
Interventions
Intervention1: Clear Aligners with probiotics: 1. Gummies(probiotics) - to be taken orally, 1 chewie per day for one week.
2. Mouthwash(probiotics) - to be taken orally, 10 ml of undiluted for 30 seco
Sponsors
Dr Vikas Thakur
Eligibility
Inclusion criteria
Inclusion criteria: Orthodontic treatment with clear aligners. Complete permanent dentition (excluding third molars) Good general health (no significant medical history or drug use during the last month). No anti inflammatory or antibiotic medications taken in the month before the study. No chewing gum or mouthwash used in the last week and during the study. Habit of brushing twice daily with prescribed fluoride toothpaste. Patient with good periodontal condition.
Exclusion criteria
Exclusion criteria: Presence of a systemic disease Smoking habit History of periodontal disease Extensive dental restorations History of antibiotics or any antibacterial mouth rinse product use during the last 6 weeks Application of professional dental hygiene procedures in the last 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Efficacy of different probiotics on biofilm formed around clear alignersTimepoint: T0- 7 days old aligners(control) T1- Probiotics gummies for 7 days T2- Probiotics rinse for 7 days (to be given after 14 days of washout period) T3- Probiotic Tablets for 7 days(to be given after 14 days of washout period) T4- Probiotics Yakult for 7 days (to be given after 14 days of washout period) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To evaluate the efficacy of different types of probiotics on biofilm formed around clear aligners using colony forming units 2. To compare the efficacy of different types of probiotics on biofilm formed around clear aligners using colony forming units 3. Quantitative analysis of biofilm formed around clear aligners after using different types of probiotics by confocal laser scanning microscopy.Timepoint: T0- 7 days old aligners(control) T1- Probiotics gummies for 7 days T2- Probiotics rinse for 7 days (to be given after 14 days of washout period) T3- Probiotic Tablets for 7 days(to be given after 14 days of washout period) T4- Probiotics Yakult for 7 days (to be given after 14 days of washout period) | — |
Countries
India
Contacts
Public ContactVikas Thakur
Institute of Dental Studies and Technologies (IDST)
Outcome results
None listed