Health Condition 1: K135- Oral submucous fibrosis Health Condition 2: C069- Malignant neoplasm of mouth, unspecified
Conditions
Interventions
Intervention1: NIL: Observational study
Control Intervention1: No agent is compared. The group for comparison will be systemically healthy patients.: Observational Case control study
Sponsors
Kasturba Medical College Manipal
Eligibility
Inclusion criteria
Inclusion criteria: Patients with early oral cancer, individuals with oral potentially malignant disorder (OPMD) and healthy individuals with tobacco exposure will be included. 1)Early oral cancer would comprise TNM stages 1 and 2. 2)Oral submucous fibrosis will be considered for OPMD 3)Healthy individuals with tobacco exposure will form the control group
Exclusion criteria
Exclusion criteria: 1. Patients on long term steroid therapy, NSAIDs or on antibiotic medication in the previous six weeks will be excluded from the study. 2. Further, those with a prior history of allergies, irradiation, chemotherapy / oncology related surgery and a history of diabetes mellitus or immune-related diseases will be excluded. 3. Pregnant and lactating women will also not be considered for the study. 4. Patients who show flu ââ?¬â?? like symptoms will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Identifying specific bacterial species showing significant variations across study groups and quantifying selected bacterial species.Timepoint: 36 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Develop a predictive modelTimepoint: 12 months | — |
Countries
India
Contacts
Public ContactDr Krishnananda Prabhu R V
Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal
Outcome results
None listed