Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: IV dexmedetomidine: Patient will receive IV dexmedetomidine, 1mcg per kg in 100ml NS over 10mins after induction with propofol and intubation.Duration of intervention will be for 10 min
Sponsors
Karnataka institute of medical sciences
Eligibility
Inclusion criteria
Inclusion criteria: Patient belonging to ASA 1 and 2 physical status giving informed valid written consent ,undergoing elective gastro/onco/ENT surgeries under general anaesthesia
Exclusion criteria
Exclusion criteria: Patient with known Cardiac, renal, neurological,psychiatric disorders,Obesity with BMI more than 30kg per metersquare,pregnant females, drug and alcohol abuse,on chronic medications such as anticonvulsant and antidepressants
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Depth of anaesthesia interested of BIS values in 3 groups that is propofol, propofol- dexmedetomidine, propofol- ketamine and to find out how addition of dexmedetomidine and ketamine to propofol can affect BISTimepoint: - Preinduction -Soon after intubation -Every 5 minutes after starting study drug infusion till the end of study period that is 10 minutes -5 minutes after completion of study drug | — |
Secondary
| Measure | Time frame |
|---|---|
| Assess hemodynamic and EtCO2 level changes with dexmedetomidine and ketamine addition to propofolTimepoint: With each reading of BIS value | — |
Countries
India
Contacts
Public ContactDr Madhuri S Kurdi
Karnataka institute of medical sciences
Outcome results
None listed