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Hyaluronic acid and vitamin C for thin gingiva

Comparative evaluation of microneedling with Hyaluronic acid injection and vitamin C injection in the management of thin gingival phenotype: A Randomised clinical study - NIL

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/08/072707
Enrollment
20
Registered
2024-08-19
Start date
Unknown
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K068- Other specified disorders of gingiva and edentulous alveolar ridge

Interventions

Intervention1: Microneedling with Vitamin C injection: Derma pen with 16 pin microneedles will be adjusted with 1.5mm depth at a mode speed of 700 cycles/min used in intermittent motion for microneedl

Sponsors

Dr Chandrima Biswas
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 18-45 years individuals with no systemic diseases, with thin gingival phenotype less than or equal to 1.5mm and presence of full mouth plaque and gingival index less than 1, with no smoking habits or no malocclusion, crowding, fillings, missing or supernumerary teeth, blood-bone conditions should be absent, presence of minimum of 20 natural teeth

Exclusion criteria

Exclusion criteria: Patients undergoing active orthodontic treatment, under antibiotics in the past 6 months, who have undergone periodontal therapy in the past 6 months, who are allergic to hyaluronic acid and vitamin C and pregnant and lactating women and who are taking blood thinners or drugs leading to gingival enlargement

Design outcomes

Primary

MeasureTime frame
1. Gingival thickness is measured using Number 15 Endodontic Spreader when inserted transgingivally. Stopper will be used as reference points and exact measurement will be recorded using endo ruler. 2. Keratinised tissue width will be measured from gingival margin to muco gingival junction using UNC 15 probe.Timepoint: Baseline, 45 days, 3 months

Secondary

MeasureTime frame
Gingival index score (Loe and Silness) and Plaque index score (Silness and Loe)Timepoint: baseline, 45 days and 3 months

Countries

India

Contacts

Public ContactDr Chandrima Biswas

Sri Rajiv Gandhi College of Dental Sciences and Hospital

umeshyadalam@gmail.com9844269511

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026