Health Condition 1: K803- Calculus of bile duct with cholangitis Health Condition 2: K804- Calculus of bile duct with cholecystitis Health Condition 3: K801- Calculus of gallbladder with othercholecystitis Health Condition 4: K802- Calculus of gallbladder without cholecystitis
Conditions
Interventions
Intervention1: tapentadol: tapentadol will be given intranasally 45 mg (22.5 mg each nostril ) 8 hourly for 24 hour
Control Intervention1: Paracetamol: IV paracetamol 1 gm infusion 8 hourly for 24 hou
Sponsors
prajnaparmita saha
Eligibility
Inclusion criteria
Inclusion criteria: All the newly diagnosed cholecystitis patients undergoing open cholecystectomy with ASA 1 & 2 at general surgery dept. of AGMC in the age group of 18 yrs and above.
Exclusion criteria
Exclusion criteria: 1.Patients with ASA Grade III or above. 2.Patients on immunosuppressive drugs. 3.Paitents unwilling for giving consent 4.Pregnant and lactating Women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Degree of analgesia by VAS scoreTimepoint: 2 hour after delivery of each analgesic dose.last analgesic dose will be administered 24 hours after cholecystectomy. Final outcome ( VAS score) will be assessed 2 hours after last analgesic dose that is 26 hours after cholecystectomy | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse effects of intranasal tapentadol & intravenous paracetamolTimepoint: 2 hours after administration of each drug dose. patients will be assessed for 24 hours after cholecystectomy | — |
Countries
India
Contacts
Public ContactPrajnaparmita Saha
Guide
Outcome results
None listed