Comparison of Pain Relief and Antibacterial Effectiveness of Nano Chitosan vs. Sodium Hypochlorite in Root Canal Treatments for Young Adults: A Randomized Controlled Trial

Evaluation of Post Operative Pain and Antibacterial Effectiveness of 0.2% Nano Chitosan and 2% Sodium Hypochlorite Irrigating Solutions in Routine Endodontic Procedure Among Young Adults: A Randomized Controlled Trial - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/08/072666

Enrollment

Registered

2024-08-19

Start date

Unknown

Completion date

Unknown

Last updated

2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K041- Necrosis of pulp

Interventions

Intervention1: Nanochitosan irrigating solution: Evaluation of post operative pain and effectiveness of 0.2% nanochitosan irrigating solution 5ml of irrigation solution is used, it is used for irriga

Eligibility

Inclusion criteria

Inclusion criteria: Single rooted teeth which are indicated for root canal treatment

Exclusion criteria

Exclusion criteria: 1.Teeth associated with the intraoral sinus. 2.Teeth associated with the extraoral sinus. 3.Presence of soft tissue swelling or abscess in relation to involved teeth. 4.History of antibiotic exposure in the previous 2 months. • Teeth with a wide or open apex • Teeth with abnormal anatomy or calcified root canals • A psychologically disturbed patient • Teeth containing vital pulp tissue. • Periodontally affected teeth.

Design outcomes

Primary

Measure	Time frame
To Evaluate Post-Operative Pain and Antibacterial Effectiveness of 0.2% Nanochitosan and 2% Sodium Hypochlorite Irrigating Solutions in Routine Endodontic Procedures Among Young Adults. Timepoint: 6, 12, 24, 48, 72Hours	—

Secondary

Measure	Time frame
1.Quantitative assessment of bacterial growth in the root canals of included participants prior to irrigation. 2.Quantitative assessment of bacterial growth in the root canals of included participants after irrigation. 3.To compare the effectiveness of 0.2% nano-chitosan & 2% sodium hypochlorite irrigating solutions on the bacteria in root canals before & after irrigation. 4.To compare the antibacterial effectiveness of 0.2% nano-chitosan & 2% sodium hypochlorite irrigating solutions. 5.To evaluate postoperative pain after endodontic treatment. Timepoint: 6, 12, 24, 48,72Hours	—

Measure

Time frame

1.Quantitative assessment of bacterial growth in the root canals of included participants prior to irrigation. 2.Quantitative assessment of bacterial growth in the root canals of included participants after irrigation. 3.To compare the effectiveness of 0.2% nano-chitosan & 2% sodium hypochlorite irrigating solutions on the bacteria in root canals before & after irrigation. 4.To compare the antibacterial effectiveness of 0.2% nano-chitosan & 2% sodium hypochlorite irrigating solutions. 5.To evaluate postoperative pain after endodontic treatment. Timepoint: 6, 12, 24, 48,72Hours

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Countries

India

Contacts

Public ContactDr Krishnaprasada L

KVG Dental college and hospital Sullia

drkpdental@yahoo.co.in9448012084

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026