Health Condition 1: K029- Dental caries, unspecified
Conditions
Interventions
Intervention1: probiotic toothpaste: Purexa Probiotic Toothpaste to be used twice daily for brushing teeth for 30 days.
Control Intervention1: Regular toothpaste: Any regular toothpaste without probi
Sponsors
Dr Twinkle Sharma
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age between 18 to 25 years. 2.Participants with all fully erupted teeth. 3.Participants with inactive caries. 4.No underlying systemic condition. 5.Habit of brushing twice daily.
Exclusion criteria
Exclusion criteria: 1.Enrolled in any other clinical trial 30 days prior to randomization. 2.With major dental conditions such as periodontal disease, dental caries and/or xerostomia or systemic diseases which could directly or indirectly affect plaque formation. 3.Using any antimicrobial mouth rinses, probiotics (unrelated to the study) antibiotics or anti-inflammatories medications within one month prior to and during the study. 4.With allergies to any ingredient present in the lorodent probiotic complex. 5.Experiencing any nausea, fever, vomiting, bloody diarrhea or severe abdominal pain within the 30 days prior to commencing the study. 6. Those who were immunocompromised and/or had a major underlying medical condition or ENT problem. 7.Had recent (within the past 45 days) or planned (within the past 90 days) surgery of any kind. 8.With a history of smoking or alcohol consumption. 9.Pregnant and lactating females. 10. Who were unable to make informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Levels of streptococcus mutans in saliva. 2.Levels of lactobacillus in saliva.Timepoint: 1.Levels of streptococcus mutans and lactobacillus in saliva at baseline 2.Levels of streptoccus mutans and lactobacillus in saliva after one month | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Change in levels of Streptococcus mutans and Lactobacillus in saliva after one month of probiotic toothpaste use.Timepoint: 1.Baseline (Day 0): Initial saliva sample collection before the start of the intervention to determine the baseline levels of Streptococcus mutans and Lactobacillus. 2.After 30 Days (Day 30): Follow-up saliva sample collection at the end of the 30-day intervention period to measure the levels of Streptococcus mutans and Lactobacillus and determine the change from baseline. | — |
Countries
India
Contacts
Public ContactDr Preety Gupta
Swami Devi Dyal Hospital and Dental College
Outcome results
None listed