Comparison of intravenous Dexmedetomidine and Midazolam as premedication in paediatric patients undergoing surgery

Comparison of effect of intravenous Dexmedetomidine and Midazolam on preoperative sedation in paediatric patients undergoing elective surgery under general anaesthesia - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/08/072649

Enrollment

Registered

2024-08-19

Start date

Unknown

Completion date

Unknown

Last updated

2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: Inj Dexmedetomidine: 1mcg/kg in 100ml NS over 10 minutes before induction Control Intervention1: Inj Midazolam: Inj Midazolam 0.05mg/kg in 100ml NS over 10 minutes before induction

Eligibility

Inclusion criteria

Inclusion criteria: Paediatric patients with ASA grade 1 undergoing elective surgery under general anaesthesia

Exclusion criteria

Exclusion criteria: 1. Obese patients with BMI more than 30 2. Patients with anticipated difficult airway 3. Patients with hepatic or renal dysfunction 4. Patients with known allergy to study drugs 5. Patients with sedation score less than 5

Design outcomes

Primary

Measure	Time frame
To compare the sedation score of IV Dexmedetomidine and MidazolamTimepoint: 0 minutes, 10 minutes, at the time of extubation and 2 hours after extubation	—

Secondary

Measure	Time frame
To compare the mask acceptance score in the two groupsTimepoint: At 10 minutes after drug administration just before induction	—

Countries

India

Contacts

Public ContactDr Nazrana Nasrin Sultana

Gauhati Medical College and Hospital

susmitaborah1971@gmail.com9435168621

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026