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Magnesium sulphate as an adjuvant for spinal anaesthesia in Preeclamptic patients : A study on its effects

Effect of addition of Magnesium sulfate as an adjuvant to intrathecal hyperbaric Bupivacaine -fentanyl in patients with preeclampsia without severe features undergoing caesarean section - A Prospective Randomized controlled study - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/08/072648
Enrollment
90
Registered
2024-08-19
Start date
Unknown
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O140- Mild to moderate pre-eclampsia

Interventions

Intervention1: Addition of magnesium sulfate to intrathecal hyperbaric bupivacaine - fentanyl: After Preanaesthetic evaluation patient meeting inclusion criteria will be selected .In operation theatre

Sponsors

Goverment Medical college Baroda
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Pregnant female with preeclampsia without severe features (systolic bp 140-160 mmhm and diastolic bp 90-110 mmhmg) 2. pregnant women with mild preeclampsia without severe features posted for elective caesarean section to be operated under spinal anaesthesia 3.pregnant women with mild preeclampsia without severe features having height ranging between 150 to 170 cm and weight ranging between 50 to 90 kg

Exclusion criteria

Exclusion criteria: 1. Patient refusal 2. Patient with contraindication to spinal anaesthesia like allergy to local anaesthetics drug ,local infection ,raised intracranial pressure, spinal deformity , coagulopathy 3.Pregnant women with coexisting systemic disorders 4.Pregnant women taking magnesium therapy 5.Eclampsia 6. Psychiatric illness 7. active labour, twin pregnancy ,complicated pregnancy

Design outcomes

Primary

MeasureTime frame
No. of Requirement of rescue analgesiaTimepoint: Till 24 hours

Secondary

MeasureTime frame
1.Duration of post operative analgesia 2.Changes in hemodynamic parameters perioperartively 3.observe spinal block characteristics 4. observe any complications like bradycardia , hypotension ,respiratory depression , pruritic , nausea , vomiting Timepoint: Till 24 hours

Countries

India

Contacts

Public ContactDr Darshna Patel

Goverment Medical college Barioda

dr.darshna1968@yahoo.com9925013155

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026