Comparative Evaluation of Two Different Formulations of Xylitol used in children with early childhood caries to see the effect on Streptococcus mutans and Candida albicans

Comparative Evaluation of Two Different Formulations of Xylitol on Streptococcus mutans and Candida albicans in Children with Early Childhood Caries: A Randomized Controlled Trial - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/08/072642

Enrollment

Registered

2024-08-19

Start date

Unknown

Completion date

Unknown

Last updated

2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K029- Dental caries, unspecified

Interventions

Intervention1: Xylitol Wipes and Xylitol Toothpaste: The intervention is done for 1 month after the enrollment of children with early childhood caries at the time of baseline. Control Intervention1: F

Eligibility

Inclusion criteria

Inclusion criteria: 1. Children aged 3-6 years. 2. Children with ECC, as per AAPD criteria 3. ASA I 4. Frankl Rating 3 & 4 5. Subjects willing to comply with the study protocol.

Exclusion criteria

Exclusion criteria: 1. Children with systemic diseases or history of recent hospitalization 2. Consumption of antibiotics in the last 3 months. 3. Children who have previously used xylitol products regularly within the last 3 months. 4. Children lacking cooperative ability.

Design outcomes

Primary

Measure	Time frame
To check the reduction in colony counts of Streptococcus Mutans and Candida AlbicansTimepoint: The outcome will be assessed at baseline, at 1 month and 2 months	—

Secondary

Measure	Time frame
To check the reduction in plaque accumulationTimepoint: It will be assessed at baseline and at 1 month	—

Countries

India

Contacts

Public ContactDr Simran Singh

ITS Dental College, Hospital and Research Centre,47 Knowledge Park, Greater Noida

mousumi87goswami@gmail.com8588854190

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026