Comparing Pain Relief Methods After Breast Cancer Surgery: Does Injecting Pain Medication Near or Deep into the Chest Muscle Work Better

Comparative evaluation of superficial and deep serratus anterior plane block for postoperative analgesia following modified radical mastectomy: a randomised controlled study - Nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/08/072633

Enrollment

Registered

2024-08-19

Start date

Unknown

Completion date

Unknown

Last updated

2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E35- Disorders of endocrine glands in diseases classified elsewhere

Interventions

Intervention1: First pain assessment will be done as soon as the patient will be awake, oriented and capable of following commands and subsequently at 2, 6, 12, 24 hours at both rest and the movement

4 – fully satisfied: The number of episodes of PONV will be recorded and rescue anti-emetic treatment will be provided with ondansetron 4 mg IV. Total postoperative opioid consumption in the first 24

4 – fully satisfied

Eligibility

Inclusion criteria

Inclusion criteria: Patient giving consent Age 18-60 years ASA Grade I and II scheduled for elective unilateral modified radical mastectomy for breast cancer

Exclusion criteria

Exclusion criteria: History of allergy to any trial drugs, presence of coagulopathy or bleeding disorders Infection at the nerve block site Chest wall deformity Body mass index more than or equal to 35kg/m2 Ingestion of any analgesic drug within 48 hours before surgery History of chronic pain medication use Trauma or history of thoracic spine surgery Sinus bradycardia

Design outcomes

Primary

Measure	Time frame
To compare the time to first rescue analgesia in two different techniques of SAP blockTimepoint: Use of first rescue analgesia after SAP block	—

Secondary

Measure	Time frame
To compare the following parameters between the two groups: ? Total intraoperative opioid (fentanyl) consumption ? Total postoperative opioid (tramadol) consumption in first 24 hours ? Pain scores(Numerical rating scale) in post-operative period at 0,2,6,12,24 hours ? Number of needle attempts ? Block performance time ? Patient satisfaction score ? Post operative nausea and vomiting (PONV) ? Any other complications Timepoint: To compare the following parameters between the two groups: ? Total intraoperative opioid (fentanyl) consumption ? Total postoperative opioid (tramadol) consumption in first 24 hours ? Pain scores(Numerical rating scale) in post-operative period at 0,2,6,12,24 hours ? Number of needle attempts ? Block performance time ? Patient satisfaction score ? Post operative nausea and vomiting (PONV) ? Any other complications	—

Measure

Time frame

To compare the following parameters between the two groups: ? Total intraoperative opioid (fentanyl) consumption ? Total postoperative opioid (tramadol) consumption in first 24 hours ? Pain scores(Numerical rating scale) in post-operative period at 0,2,6,12,24 hours ? Number of needle attempts ? Block performance time ? Patient satisfaction score ? Post operative nausea and vomiting (PONV) ? Any other complications Timepoint: To compare the following parameters between the two groups: ? Total intraoperative opioid (fentanyl) consumption ? Total postoperative opioid (tramadol) consumption in first 24 hours ? Pain scores(Numerical rating scale) in post-operative period at 0,2,6,12,24 hours ? Number of needle attempts ? Block performance time ? Patient satisfaction score ? Post operative nausea and vomiting (PONV) ? Any other complications

—

Countries

India

Contacts

Public ContactDr Hemlata

King Georges Medical University Lucknow

hema2211@yahoo.co.in9415410236

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026