Comparison and Evaluation of different statins in post menupausal women with Chronic Periodontitis

Sub-gingival delivery of 1.2% Simvastatin and 1.2%Rosuvastatin thermosensitive gel for the treatment of Chronic periodontitis in post - menopausal women - Clinical and Immunological study: A Randomized Control Trial - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/08/072625

Enrollment

Registered

2024-08-19

Start date

Unknown

Completion date

Unknown

Last updated

2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Local Drug Delivery: Scaling and Root Planing, Recording of clinical parameters,Saliva samples and Radiographs,Local Drug delivery.Follow up at baseline,3 months and 6 months for improv

Eligibility

Inclusion criteria

Inclusion criteria: Post Menopausal Women with pocket depth more than equal to 5 or clinical attachmeny levels more than equal to 4 or vertical bone loss on Radiographs ,with no history of previous periodontal Therapy.

Exclusion criteria

Exclusion criteria: patients with known systemic dseases,aggresive periodontitis,patients allergic to statins,tobacco users,immunocomromised patients

Design outcomes

Primary

Measure	Time frame
To evaluate the clinical parameters after the local drug delivery Timepoint: 3 months	—

Secondary

Measure	Time frame
To evaluate the bone fill radiographically after the local drug deliveryTimepoint: 6 months	—

Countries

India

Contacts

Public ContactAnita Singh

JSS DENTAL COLLEGE AND HOSPITAL

sumanbv_72@yahoo.co.in9945551564

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026