Effect of laser light therapy and exercises on mouth ulcer, cancer related muscle loss and tiredness in head and neck cancer patients on chemoradiotherapy

Effectiveness of photo biomodulation and exercise based rehabilitation on oral mucositis pain, sarcopenia and cancer-related fatigue in Head and Neck cancer patients on chemoradiotherapy - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/08/072614

Enrollment

100

Registered

2024-08-19

Start date

Unknown

Completion date

Unknown

Last updated

2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C021- Malignant neoplasm of border of tongue Health Condition 2: C102- Malignant neoplasm of lateral wallof oropharynx

Interventions

Intervention1: Photo biomodulation and exercise based rehabilitation to head and neck cancer patients on chemoradiotherapy: photobiomodulation protocol for sarcopenia includes providing scanning laser

Eligibility

Inclusion criteria

Inclusion criteria: Patients with Head and Neck cancer on chemoradiotherapy Asian Working Group of Sarcopenia 2019 criteria

Exclusion criteria

Exclusion criteria: Patients with end-stage cancer receiving palliative treatment Metastatic cancers Any absolute/ relative contraindications to perform 6 Minute Walk Test ECOG (Eastern Cooperative Oncology Group) score: 3-5 Post-operative patients

Design outcomes

Primary

Measure	Time frame
Sarcopenia: Circumference measurement (calf circumference male:34cm, female: 33cm) Body composition: Body composition analyzer. Grip strength: handheld dynamometer Physical Performance: Timed up and go test Functional mobility: Short physical performance battery Oral mucositis: Oral mucositis grade: EORTC Oral mucositis grading scale Oral mucositis pain: NPRS Timepoint: Baseline After 4th week After 12th week After 24th week	—

Measure

Time frame

Sarcopenia: Circumference measurement (calf circumference male:34cm, female: 33cm) Body composition: Body composition analyzer. Grip strength: handheld dynamometer Physical Performance: Timed up and go test Functional mobility: Short physical performance battery Oral mucositis: Oral mucositis grade: EORTC Oral mucositis grading scale Oral mucositis pain: NPRS Timepoint: Baseline After 4th week After 12th week After 24th week

—

Secondary

Measure	Time frame
Fatigue: Using Fatigue Severity Scale Functional capacity: Using 6MWT Quality of life: Using EORTC QLQ H&N43 Blood parameters: Hemoglobin and platelet levelsTimepoint: Baseline After 4th week After 12th week After 24th week	—

Countries

India

Contacts

Public ContactDr G Arun Maiya

Manipal College of Health Professions Manipal

grace1.mchpmpl2023@learner.manipal.edu917406148321

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026