Health Condition 1: H188- Other specified disorders of cornea
Conditions
Interventions
Intervention1: Chloroquine 0.03% eye drops: Topical eye drops two times a day for one month.
Control Intervention1: Cyclosporine 0.05% eye drops: Topical eye drops two times a day for one month.
Contr
Sponsors
Dr Ekroop Kaur
Eligibility
Inclusion criteria
Inclusion criteria: Patients with symptoms of moderate to severe dry eye. Patients with findings of dry eye on slit lamp examination.
Exclusion criteria
Exclusion criteria: Patients with history of ocular surgery or ocular trauma in last 2 months. Patients with history of contact lens use in last 2 months. Patients with active ocular disease other than dry eye like uveitis, keratitis, conjunctivitis etc. Patients allergic to fluorescein stain. Patients with history of allergy to either of the test drugs. Patients unable to undergo Schirmer’s test or slit lamp examination and hence TBUT. Patients unable to understand regional language or English and hence understand OSDI questionnaire. Pregnant females.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assessment and comparison of clinical efficacy of topical chloroquine 0.03% versus topical cyclosporine 0.05% in patients with moderate to severe dry eye disease by means of testing for Schirmer test, Tear film breakup time and OSDI score.Timepoint: 1 month | — |
Secondary
| Measure | Time frame |
|---|---|
| NILTimepoint: NIL | — |
Countries
India
Contacts
Public ContactDR EKROOP KAUR
Guru Gobind Singh Medical College and Hospital, Faridkot 151203, Punjab, India
Outcome results
None listed