Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: HDR curve method for Heparin dose determination before going on CPB: In HDR group, a dose of 2mg/kg heparin is administered intravenously after sternotomy. A timer which is available in
Sponsors
AIIMS NEW DELHI
Eligibility
Inclusion criteria
Inclusion criteria: Pediatric cardiac surgical patients less than 14 years old posted for elective cardiac surgery on cardiopulmonary bypass.
Exclusion criteria
Exclusion criteria: Patients who refuse to participate in the study Emergency surgery Redo surgery Patients with allergy to Heparin or Protamine Renal dysfunction Severe liver disease CPB time more than 180 minutes Patients on preoperative anticoagulants Patients greater than 14 years of age
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To ascertain whether or not heparin dose administered as determined by HDR curve achieves target ACT of 480 before CPB.Timepoint: Before going on bypass. | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare total dose of heparin given in both the groups. To compare protamine dose administered in both the groups. To compare amount of postoperative blood loss between the study groups. Timepoint: Intraoperative and post operative | — |
Countries
India
Contacts
Public ContactDr Sandeep Chauhan
AIIMS New Delhi
Outcome results
None listed