PECS2 block versus Serratus Plane Block for post-operative pain in breast cancer surgery patients.

Single shot Pectoral Plane Block type2 (PECS2 Block) versus Serratus Plane Block for Postoperative analgesia in breast cancer surgery: To assess the effects of these two blocks on postoperative acute and long term pain. - nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/08/072584

Enrollment

Registered

2024-08-16

Start date

Unknown

Completion date

Unknown

Last updated

2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C509- Malignant neoplasm of breast of unspecified site

Interventions

Intervention1: SAPB block: The local anaesthetic, total dose of 30ml of 0.25% Bupivacaine is injected anteriorly to the serratus anterior. Duration of intervention: 15-20 mins Frequency of intervent

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA grade I to III fit patients. 2. Ages between 18-65 years of gender female. 3. Patients undergoing breast cancer surgery: simple mastectomy, modified radical mastectomy, radical mastectomy. 4. Hemodynamically stable patients with all routine investigations within normal limits without any other comorbidities. 5. Patients who are not on any cardiac drugs. 6. Availability of informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with ASA physical status IV and above. 2. Patients below 18 years and above 65 years of age. 3. Patient posted for emergency procedures. 4. Patients with major neurological, cardiac, respiratory, metabolic, renal. Hepatic disease with coagulation abnormalities. 5. Patients with cardiac comorbidities. 6. Patient refusal.

Design outcomes

Primary

Measure	Time frame
To evaluate and compare the effect of single shot pectoral plane block and serratus plane block for postoperative analgesia following breast cancer surgery.Timepoint: The VAS will also be recorded to assess effect on pain at interval of postoperative 0 hours, 4 hours, 8 hours, 12 hours, 24 hours and 48hours and day5, day 15, day 30 and day 60.	—

Secondary

Measure	Time frame
1. To asses and compare the efficacy of PECS 2 block and serratus plane block for postoperative analgesia. 2. Duration of postoperative analgesia in PECS2 and Serratus plane block. 3. To asses efficacy of PECS-2 & Serratus plane block for postoperative analgesia for acute pain 4. Number of rescue analgesics required in the first 48 hour period. 5. To assess efficacy of PECS-2 & Serratus plane block for post-surgical chronic pain (2months). 6. Adverse effects of the block, and if any its management.Timepoint: The VAS will also be recorded to assess effect on pain at interval of postoperative 0 hours, 4 hours, 8 hours, 12 hours, 24 hours and 48hours and day5, day 15, day 30 and day 60.	—

Measure

Time frame

1. To asses and compare the efficacy of PECS 2 block and serratus plane block for postoperative analgesia. 2. Duration of postoperative analgesia in PECS2 and Serratus plane block. 3. To asses efficacy of PECS-2 & Serratus plane block for postoperative analgesia for acute pain 4. Number of rescue analgesics required in the first 48 hour period. 5. To assess efficacy of PECS-2 & Serratus plane block for post-surgical chronic pain (2months). 6. Adverse effects of the block, and if any its management.Timepoint: The VAS will also be recorded to assess effect on pain at interval of postoperative 0 hours, 4 hours, 8 hours, 12 hours, 24 hours and 48hours and day5, day 15, day 30 and day 60.

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Countries

India

Contacts

Public ContactKshitija Devendra Bora

DY Patil University

draparnabagle@gmail.com9422710943

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026