Efficacy of upper limb block using Local Anaesthetic for orthopedic surgery

To evaluate efficacy of hyaluronidase as an adjuvant to bupivacaine on the quality of brachial plexus block via sonar guided supraclavicular approach: A prospective randomized comparative study in department of Anesthesia ,sms medical college, jaipur . - Nil

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/08/072579

Enrollment

Registered

2024-08-16

Start date

Unknown

Completion date

Unknown

Last updated

2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M859- Disorder of bone density and structure, unspecified

Interventions

Intervention1: Brachial plexus block by supraclavicular approach.: Patient will receive 25 ml of 0.5% plain Bupivacaine by single injection technique. Total volume 25 ml. Control Intervention1: Brac

Eligibility

Inclusion criteria

Inclusion criteria: Undergoing elective upper limb surgeries. Patients willing to participate with written informed concent Patient of either sex All Adults American Society of Anesthesiologists(ASA) grade 1 and 2 Body weight between 40-70 kg.

Exclusion criteria

Exclusion criteria: Case with sepsis, bacteremia or skin infection of local site History of severe hypovolemia, anemia and compromised Renal ,cardiac and respiratory system Patient allergic to drugs used for study. Failure of supraclavicular block cases in which general Anesthesia will be required.

Design outcomes

Primary

Measure	Time frame
Mean of Onset of sensory block (minutes) Mean of Onset of motor block (minutes) Mean Duration of motor block (minutes) Proportion of Rate of success of block Mean Duration of analgesia (minutes) Mean Hemodynamic parameters Proportion of cases having Complication( if any) Timepoint: Baseline, 2 min 5 min 10 min 15 min 30 min	—

Secondary

Measure	Time frame
Mean of Onset of sensory block (minutes) Mean of Onset of motor block (minutes) Mean Duration of motor block (minutes) Proportion of Rate of success of block Mean Duration of analgesia (minutes) Mean Hemodynamic parameters Proportion of cases having Complication( if any) Timepoint: Baseline 2 min 5min 10min 15min 30min	—

Countries

India

Contacts

Public ContactRinki meena

Sms medical college

drsonalisms@gmail.com9214540552

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026