Comparison of two types of intravenous fluid therapy in bowel obstruction surgery

Comparison of effect of plasmalyte and ringer lactate on acid base status and lactate in patients undergoing emergency gastrointestinal obstruction surgery- A pragmatic randomised control trial - Nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/08/072561

Enrollment

110

Registered

2024-08-16

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: K566- Other and unspecified intestinal obstruction

Interventions

Intervention1: Plamalyte: Plamalyte arm receives plasmalyte as only fluid throughout surgery. Control Intervention1: Ringer lactate infusion: Infusion will be administered throughout the surgery

Eligibility

Inclusion criteria

Inclusion criteria: ASA 1,2,3 physical status. Patients undergoing emergency gastro intestinal obstruction surgery.

Exclusion criteria

Exclusion criteria: Mechanical ventilation Inotropes Acute or chronic kidney disease

Design outcomes

Primary

Measure	Time frame
To determine and compare the effect of plasmalyte and ringer lactate on post operative PH, Strong ion difference and lactate in patients undergoing emergency gastro intestinal obstruction surgeryTimepoint: 1 hour after surgery, 24 hour after surgery, at the time discharge	—

Secondary

Measure	Time frame
To compare the effect on acute kidney injury marker (kidney injury molecule -1 ) To compare the effect of predefined composite of renal, cardiovascular and respiratory system complicationsTimepoint: At the end of study .(2 years approx)	—

Countries

India

Contacts

Public ContactAjay Kumar Jha

JIPMER, Puducherry

drajaykjha@rediffmail.com09868477642

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026