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Compare and see which drug is good for pain relief in patients undergoing modified radical mastectomy

Comparison between ketamine hcl, magnesium sulphate, paracetamol as pre-emptive analgesia in patients undergoing modified radical mastectomy for post operative analgesia: a prospective randomized double blind clinical trail - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/08/072560
Enrollment
90
Registered
2024-08-16
Start date
Unknown
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: inj KETAMINE HCL 0.5 mg: Patients receiving Ketamine 0.5 mg/kg in 100ml NS as premedication 10 min before surgery Control Intervention1: Inj. Paracetamol 15-20 mg/kg: Patients receiving

Sponsors

Dr Pooja V
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Female patients in the age group of 18 - 70 years Patients of ASA grade 1 and 2 Patients scheduled for carcinoma breast surgeries

Exclusion criteria

Exclusion criteria: Patients’ refusal to participate in study History of diabetes mellitus and hypertension, epilepsy, cerebrovascular accident, increased intracranial pressure Allergic to study drugs, substance abuse, neuropsychiatric illness, chronic pain medications, not able to communicate.

Design outcomes

Primary

MeasureTime frame
To access post operative analgesia through Visual Analogue Scale score in patient undergoing Modified Radical Mastectomy (MRM) surgery. Timepoint: 30 mins after extubation, 2hrs, 4hrs, 8hrs, 12hrs, 24hrs—

Secondary

MeasureTime frame
Haemodynamic changes Total dose of rescue analgesia consumed in 24 hrs Postoperative sedation score Side effects (post operative nausea or vomiting, respiratory depression, hallucinations, hypotension, bradycardia)Timepoint: 30 mins after extubation, 2hrs, 4hrs, 8hrs, 12hrs, 24hrs—

Countries

India

Contacts

Public ContactDr Pooja V

Indira Gandhi Institute of Medical Sciences

drvvinodv@gmail.com8292000111

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026