Study for assessing the better intra-articular injection for the treatment of mild to moderate knee arthritis

Intra-articular Platelet Rich Plasma vs. Corticosteroid vs. Hyaluronic Acid in the Treatment of Mild and Moderate Osteoarthritis of knee - Nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/08/072559

Enrollment

105

Registered

2024-08-16

Start date

Unknown

Completion date

Unknown

Last updated

2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M179- Osteoarthritis of knee, unspecified

Interventions

Intervention1: 6 ml of Autologous platelet rich plasma: Intra-articular injection given into the joint space. Control Intervention1: 6 ml of Hyaluronic acid: Intra-articular injection given into the j

Eligibility

Inclusion criteria

Inclusion criteria: Patient having old to moderate osteoarthritis of knee (kellgran lawrence classification grades 1,2,&3) . All patients above the age of 45 years

Exclusion criteria

Exclusion criteria: Patients having secondary osteoarthritis of knee, having history of any previous knee surgeries for ligaments injuries / intra articular fractures. Any history of infections like TB/bacterial (post Septic Sequelae ).

Design outcomes

Primary

Measure	Time frame
Assessment of pain relief by the Visual Analogue Score (VAS). Where 0 points equal to no pain and 10 points equal to worst painTimepoint: 1 month, 3months, 6 months, 12 months.	—

Secondary

Measure	Time frame
Variations in the WOMAC scores ( Western Ontario and McMaster Universities Arthritis Index ) Where 0 points gives the best outcome and 96 points gives the worst outcomeTimepoint: 1 month, 3months, 6 months, 12 months.	—

Countries

India

Contacts

Public ContactDr E Dilip Kumar Naidu

SRM Institute of Science and Technology

erraguntladilipnaidu@gmail.com9884460536

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026