Comparing between diaphragmatic and parasternal muscle thickness using Ultrasonography for predicting weaning in intubated patients.

Comparative analysis of diaphragmatic thickness fraction with parasternal muscle thickness fraction by the use of ultrasonography for predicting weaning in adults receiving mechanical ventilation. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/08/072553

Enrollment

Registered

2024-08-16

Start date

Unknown

Completion date

Unknown

Last updated

2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: ultrasonography of diaphragmatic thickness thickness: three readings of diaphragmatic muscle thickness will be recorded twice daily once the patient receiving ventilatory support is put

Eligibility

Inclusion criteria

Inclusion criteria: All the patients with age more than 18 years patients receiving mechanical ventilation in process of weaning from the same

Exclusion criteria

Exclusion criteria: Patients with following will be excluded from the study Diaphragmatic paralysis/injury, neuromuscular disease, pregnant women, lactating/nursing mothers Patients aged less than 18 years. Received mechanical ventilation for less than 24 hrs. Preexisting diaphragm disease. Any breach in skin preventing DUS examination in subcostal area. Phrenic nerve palsy. Refusal of consent

Design outcomes

Primary

Measure	Time frame
Comparison of diaphragmatic thickness with parasternal muscle thickness using ultrasonography for predicting weaning in patients receiving mechanical ventilation in ICU usg measured diaghragmatic muscle thickess fraction and parasternal thickness fraction will be measured and the outcomes of two will be compared in all patients Timepoint: From starting of weaning process at predefined time intervals every day twice moring and evening till 24 hours post successful extubation diaphragmatic and parasternal muscle thickness will be measured using ultrasound. 3 readings each in morning and evening will be taken for both diaphragmatic and parasternal muscle thickness.	—

Measure

Time frame

Comparison of diaphragmatic thickness with parasternal muscle thickness using ultrasonography for predicting weaning in patients receiving mechanical ventilation in ICU usg measured diaghragmatic muscle thickess fraction and parasternal thickness fraction will be measured and the outcomes of two will be compared in all patients Timepoint: From starting of weaning process at predefined time intervals every day twice moring and evening till 24 hours post successful extubation diaphragmatic and parasternal muscle thickness will be measured using ultrasound. 3 readings each in morning and evening will be taken for both diaphragmatic and parasternal muscle thickness.

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Secondary

Measure	Time frame
1. To measure diaphragm movement derived parameters i.e .Amplitude [AMP] in centimeters (cm), thickness of muscle during inspiration and expiration. 2. To measure parasternal muscle derived parameters i.e thickness of muscle during inspiration and expiration. 3. To observe the values of Rapid Shallow Breathing Index,Negative Inspiratory Force & occlusion pressure during weaning. 4. To compare the sensitivity,specificity ,positive predictive value, negative predictive value and length of stay with all parametersTimepoint: From starting of weaning process till 24 hours post successful extubation. 3 readings of morning evening and night each day.	—

Measure

Time frame

1. To measure diaphragm movement derived parameters i.e .Amplitude [AMP] in centimeters (cm), thickness of muscle during inspiration and expiration. 2. To measure parasternal muscle derived parameters i.e thickness of muscle during inspiration and expiration. 3. To observe the values of Rapid Shallow Breathing Index,Negative Inspiratory Force & occlusion pressure during weaning. 4. To compare the sensitivity,specificity ,positive predictive value, negative predictive value and length of stay with all parametersTimepoint: From starting of weaning process till 24 hours post successful extubation. 3 readings of morning evening and night each day.

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Countries

India

Contacts

Public ContactDr Sanjeev Palta

Govenment medical college and hospital, Sector 32-B Chandigarh P.O-160030 India

richajayant@rediffmail.com9646121513

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026