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Comparison of the effectiveness of Intralesional Methotrexate with Intralesional Triamcinolone Acetonide in the treatment of Localized patchy hair loss of the scalp.

Comparison of the effectiveness of Intralesional Methotrexate with Intralesional Triamcinolone Acetonide in the treatment of Localized Alopecia Areata of the scalp - A Randomized controlled Trial.

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/08/072542
Enrollment
70
Registered
2024-08-16
Start date
Unknown
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: L63- Alopecia areata

Interventions

Intervention1: Intralesional Methotrexate: I/L Methotrexate (25mg/ml ) (Max.dose-5mg) sessions will be repeated every 3 weeks for maximum three sessions and patients will be assessed on each f

Sponsors

Karthiyaini A
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Adult patients with Localized Alopecia Areata of the scalp with = 3 patches 2.Patients who did not receive any specific treatment for Alopecia Areata or regrowth of hair during the last 3 months.

Exclusion criteria

Exclusion criteria: 1.Pregnant and lactating women 2.Chronic hepatic or hematological disorders 3.Patients on systemic corticosteroids or other Immunosuppressants 4.Local infections

Design outcomes

Primary

MeasureTime frame
To Compare the effectiveness of Intralesional Methotrexate and Intralesional Triamcinolone Acetonide in the treatment of localized Alopecia areata of the scalp clinically using SALT score and Regrowth scale. Timepoint: Sessions will be repeated every 3 weeks for maximum three sessions(0,3,6weeks) and patient will be evaluated at 9th week and12th week.

Secondary

MeasureTime frame
To compare the Trichoscopic changes following treatment of localized alopecia areata of scalp with Intralesional Methotrexate & Intralesional Triamcinolone Acetonide.Timepoint: Sessions will be repeated every 3 weeks for maximum three sessions(0,3,6weeks) & patient will be evaluated at 9th week and12th week.

Countries

India

Contacts

Public ContactKARTHIYAINI A

Aarupadai Veedu medical college and hospital,Pondicherry

sheela.kuruvila@avmc.edu.in9047038527

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026