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Preventing post operative sore throat in patients,comparison of two drugs

To determine the efficacy of dexmedetomidine and dexamethasone nebulisation in preventing sore throat in patients undergoing general anesthesia: A randomised double blind comparative study - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/08/072540
Enrollment
63
Registered
2024-08-16
Start date
Unknown
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Dexmeditomidine: Nebulization with dexmedetomidine given pre operatively to patients posted for general anesthesia for endotracheal intubation at a dose of 50 mcg/ml with 4ml normal sal

Sponsors

Rajarajeswari Medical College and Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.ASA I and II patients of either sex 2.Patients aged between 18 to 60years 3.Patients undergoing elective surgeries under general anaesthesia with endotracheal intubation

Exclusion criteria

Exclusion criteria: 1.History of allergy to study drug. 2.Pre operative sore throat 3.Upper respiratory infection or COPD 4.Pregnancy 5.Anticipated difficult airway 6.Cormack and Lehane grade are 3 or 4, duration of laryngoscopy more than 15 seconds,more than one intubation attempts 7.Intraoperative deterioration preventing extubation 8.Anesthesia lasting over two hours 9. Naso gastric tube insertion

Design outcomes

Primary

MeasureTime frame
study is to evaluate and compare the efficacy of dexmedetomidine and dexamethasone nebulisation in preventing sore throat in patient undergoing general anesthesiaTimepoint: 0 hour, 2hours ,4hours ,6hours 12hours and 24hours post operative

Secondary

MeasureTime frame
study side effects such as dry mouth, cough, PONV, hemodynamic instability.Timepoint: 24hours post operative

Countries

India

Contacts

Public ContactDr Shruthi KS

Rajarajeswari Medical College and hospital

dr.nadia.rose@gmail.com9945353471

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026