Health Condition 1: - Health Condition 2: O- Medical and Surgical Health Condition 3: O- Medical and Surgical
Conditions
Interventions
Intervention1: inj remifentanyl: patients in Group R will receive IV remifentanil as 1 mcg/kg bolus over 45 sec followed by 0.2 mcg/kg/min.
Control Intervention1: inj dexmeditomidine: Patients in Grou
Sponsors
Dr Annu Choudhary
Dr Swati Singh
Eligibility
Inclusion criteria
Inclusion criteria: Patients with Primary Hypertension Grade 1 & 2, ASA II, posted for elective surgery under general anaesthesia
Exclusion criteria
Exclusion criteria: • Patient’s refusal to participate • Uncompensated cardiovascular, pulmonary, neurological, hepato-renal, endocrine disorders • Allergy to study drugs • Any substance abuse disorders. • Viral marker status positive
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| change in BIS values on laryngoscopyTimepoint: immediately after intubation (Ti) | — |
Secondary
| Measure | Time frame |
|---|---|
| Comparison of time to achieve BIS 50 in between two groups 2. Comparison of total propofol consumption for induction in between the two groups 3. Incidence of any adverse effects in two groups 4. Comparison of change in vital parameter ( HR, MAP,SpO2, RR) Timepoint: Baseline (0min) 1 min 2 min 3 min 4 min 5 min 6 min 7 min 8 min 9 min 10 min Before induction After induction Before laryngoscopy After intubation (Ti) 5 min 10 mins 30 min 60 min end of surgery | — |
Countries
India
Contacts
Public ContactDr Annu Choudhary
Indira Gandhi institute of medical sciences, Patna
Outcome results
None listed