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Using bone grafts to treat individuals with gum diseases who have bone defects

Comparative evaluation of the clinical and radiographic outcomes of Nanohydroxyapatite bone graft with and without Chitosan Nanohydrogel in periodontal bony defects A randomized clinical trial - NIL

Status
Recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/08/072510
Enrollment
30
Registered
2024-08-14
Start date
Unknown
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Periodontal bony defects will be treated by using nanohydroxyapatite bone graft with chitosan nanohydrogel: The entire procedure will be performed under local anesthesia and aseptic con

Sponsors

BODIMALLA SANDHYA
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients who are systemically healthy. Both males and females with age = 30 years having periodontitis with bilateral similar bony defects. Pocket depths =5mm after phase I evaluation Bilateral bony defect of depth = 2mm measured with CBCT. Radiographic evidence of bone loss. Absence of periapical pathology. Participants who are co-operative and able to come for regular follow-up.

Exclusion criteria

Exclusion criteria: who will be known to have a systemic condition, those taking antiresorptive medicines or immunosuppressants or corticosteroids. Patients with poor oral hygiene, Patients those with a history of unfavourable oral habits. Patients who underwent periodontal therapy in the past six months, Pregnant or nursing mothers. Individuals who are known allergic to chitosan products or graft components Medically compromised or under therapeutic regimen that may alter the probability of periodontal healing. Use of tobacco in any form.

Design outcomes

Primary

MeasureTime frame
To compare the changes in amount of bone fill and percentage of bone fillTimepoint: Baseline and 6 months

Secondary

MeasureTime frame
To compare change in Probing depth (PD), Clinical attachment level (CAL) and Gingival bleeding index. Timepoint: Baseline , 1month and 6 months

Countries

India

Contacts

Public ContactDR SREENIVAS NAGARAKANTI

Narayana Dental College and Hospital

sreenivasnagarakanti@gmail.com9985664566

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026