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Infusion B vitamin-containing Optineuron improves energy metabolism and lowers lactate accumulation, which can help patients having surgery with a Cardio Pulmonary Bypass Machine experience less lactic acidosis.

Role of Injection Optineuron on serum lactate levels in a patient undergoing surgery on Cardio Pulmonary Bypass Machine - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/08/072508
Enrollment
192
Registered
2024-08-14
Start date
Unknown
Completion date
Unknown
Last updated
2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I088- Other rheumatic multiple valve diseases

Interventions

Intervention1: Injection optineuron: Injection Optineuron, containing B vitamins, may mitigate lactic acidosis during surgery with a Cardio Pulmonary Bypass Machine by promoting cellular metabolism an

Sponsors

Operation Theater Intensive Care Unit
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All patients going for Valvular surgeries with Cardio Pulmonary Bypass time more than 60 mins

Exclusion criteria

Exclusion criteria: Patients with high pre operative lactate levels. Coronary Artery Disease. Uncontrolled Diabetes Mellitus type – 2. Peripheral Vascular Disease. Stroke. Liver disease. Cardio Pulmonary bypass time less than 60 mins.

Design outcomes

Primary

MeasureTime frame
To decrease lactate levels in patients undergoing surgery post Cardio Pulmonary BypassTimepoint: To decrease lactate levels in patients undergoing surgery post Cardio Pulmonary Bypass—

Secondary

MeasureTime frame
To decrease post operative ionotropic support & ICU stay in patients undergoing surgery on Cardio Pulmonary Bypass machineTimepoint: 2hrs to 48hrs—

Countries

India

Contacts

Public ContactProf Vinita Singh

King Georges Medical University Lucknow

drvinitasingh70@gmail.com9415080782

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026