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Impact on intraoperative blood pressure and heart rate during surgery with propofol versus sevoflurane anesthesia.

Propofol Total Intravenous Anaesthesia versus Sevoflurane Inhalational Anaesthesia on Haemodynamic Response Profile during Suspension Laryngoscopy in Adults undergoing Micro laryngeal Surgery.A Randomized Controlled Trial. - Nil

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/08/072486
Enrollment
42
Registered
2024-08-13
Start date
Unknown
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Propofol: Patients will receive intravenous propofol for both induction and maintenance of anaesthesia intraoperatively. After intubation, in the propofol group, the TCI-pump (Alaris p

Sponsors

Sir Ganga Ram Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with laryngeal pathology undergoing microlaryngeal surgery (MLS) ASA physical status I and II

Exclusion criteria

Exclusion criteria: 1. ASA GR III AND IV (uncompensated cardiovascular, hepatic, or renal disease) 2. Psychiatric or neurological disorder 3. Uncontrolled endocrine disease (diabetes mellitus, hypothyroidism) 4. Known allergy or hypersensitivity to the study drug. 5. Drug dependence or substance abuse 6. Refusal to informed consent.

Design outcomes

Primary

MeasureTime frame
Haemodynamic changes during suspension laryngoscopy (heart rate, Systolic blood pressure)Timepoint: At pre-induction, post-induction, post endotracheal intubation, every 3 minutes post insertion of rigid laryngoscope till its removal and every 30 minutes (for first 2 hours)

Secondary

MeasureTime frame
Frequency of adverse haemodynamic effects Use of rescue drugs for maintaining haemodynamicsTimepoint: pre induction, post-induction, post endotracheal intubation, every 3 minutes post insertion of rigid laryngoscope till its removal & every 30 minutes (for first 2 hours)

Countries

India

Contacts

Public ContactDr Prabhat Kumar Choudhary

Institute of Anaesthesiology, Pain & Perioperative Medicine

anagharjv0405@gmail.com9789957623

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026