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A Comparison Of Clinical Effect Of Ketamine Versus Fentanyl When Given In Combination With Propofol And Midazolam In Dilatation And Curettage Cases.

Comparison Study Of Recovery Characteristics And Clinical Effect Of Ketamine Vs Fentanyl As An Adjuvant To Propofol And Midazolam In Dilatation And Curettage : A Randomized Double-Blind Interventional Study. - nil

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/08/072483
Enrollment
62
Registered
2024-08-13
Start date
Unknown
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O029- Abnormal product of conception, unspecified

Interventions

Intervention1: Total Intravenous Anaesthesia: Patient will be randomly divided into two groups. Group A: Fentanyl , Midazolam , Propofol will be taken. Group B : Ketamine , Midazolam , Propofol will

Sponsors

Heritage Institute Of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA physical status classification I- II 2. Patients who were scheduled for Dilation & Curettage procedures.

Exclusion criteria

Exclusion criteria: 1. ASA physical status class III-IV 2. Allergic to study drugs 3. Patients denying consent for study. 4. Body mass index = 35 kg/m2. 5. Chronic use of sedatives or opioid analgesics, and presence of a psychiatric disorder with chronic medical treatment, presence of liver or kidney dysfunctions, cardiac and endocrine diseases . 6. Non-cooperative patients.

Design outcomes

Primary

MeasureTime frame
To compare difference in Mean Modified Aldrete’s score & post-operatively and mean recovery time taken.Timepoint: AT 30 min, 1hour , 2 hour, 4 hrs & 6 hrs

Secondary

MeasureTime frame
1) To evaluate difference in change in hemodynamic parameters during intra-operative from baseline 2) To assess difference in mean time duration taken for need for first rescue analgesia in both group. 3) To assess difference in % of cases who will experience side effects within 6 hours.Timepoint: 1) From 1minutes,5,10,15,20, 25minutes and 30 minutes during intra-operative period.

Countries

India

Contacts

Public ContactDr. ANKUR KUMAR

Heritage Institute of medical Sciences, varanasi

akhil61086@rediffmail.com9582113920

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026