Health Condition 1: C148- Malignant neoplasm of overlappingsites of lip, oral cavity and pharynx
Conditions
Interventions
Control Intervention1: NIL: NIL
Sponsors
Sri Venkateshwara Institute of medical sciences
Eligibility
Inclusion criteria
Inclusion criteria: 1. Head and neck squamous cell carcinomas Stage I â?? IVb (AJCC Staging 8th Edition) (14) (American joint Committee on Cancer) requiring definitive CRT/ Adjuvant CRT 2. Various sites of HNC including oral cavity, oropharynx nasopharynx & hypopharynx 3. Age : 18 years and above 4. Eastern Cooperative Oncology Group (ECOG) Performance Status Scale (PSS) â?? 0-2 5. Patients who have given approval for informed written consent
Exclusion criteria
Exclusion criteria: •Patients with distant metastasis Stage IV C •ECOG PSS â?? 3 - 4 •Previous RT to the head-and-neck region •Lack of a pre-radiation audiometry •Patients with Congenital/ acquired hearing loss •Pregnant and Lactating mothers
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of sensorineural hearing loss by Pure tone AudiometryTimepoint: Day 1 to 3 months after treatment | — |
Secondary
| Measure | Time frame |
|---|---|
| To find the correlation between the cumulative dose of cisplatin to the various degrees of SNHL and severity of SNHL at different frequencies. Timepoint: Day 1 to 3 months after treatment | — |
Countries
India
Contacts
Public ContactDr Pranabandhu das
Sri venkateswara institute of medical sciences
Outcome results
None listed