Health Condition 1: C069- Malignant neoplasm of mouth, unspecified
Conditions
Interventions
Intervention1: Saliva telomere length: Unstimulated saliva will be collected from the patients having leukoplakia. DNA isolation will be done and qPCR will be conducted.
Intervention2: salivary telome
Sponsors
Dr Anoushka Chauhan
Eligibility
Inclusion criteria
Inclusion criteria: Individuals diagnosed with oral leukoplakia. Patients with histologically confirmed or diagnosed with oral squamous cell carcinoma. Normal individuals without any oral lesions, matched for age and gender.
Exclusion criteria
Exclusion criteria: Individuals with a history of other malignancies. Patients with known immunodeficiency or autoimmune disorders. Pregnant or lactating individuals.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To measure the telomere length in saliva samples from individuals with leukoplakia, individuals with oral squamous cell carcinoma (OSCC), and healthy controls.Timepoint: At first visit- baseline | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the salivary telomere lengths between these groups. To determine the diagnostic potential of salivary telomere length in distinguishing between healthy individuals, leukoplakia patients, and OSCC patients. Timepoint: At first visit- baseline | — |
Countries
India
Contacts
Public ContactDr Anoushka Chauhan
Kahers Kle Vk Institute of Dental Sciences
Outcome results
None listed