Health Condition 1: K051- Chronic gingivitis Health Condition 2: A488- Other specified bacterial diseases
Conditions
Interventions
Intervention1: "Gold Nanoparticle-Coated Orthodontic Retainers.": reating Gold Nanoparticles: Synthesizing GNPs from pomegranate peel extract.
Coating Retainers: Applying these nanoparticles to thermo
Sponsors
Krishna Vishwa Vidyapeeth
Eligibility
Inclusion criteria
Inclusion criteria: The inclusion criteria for this study involve patients with permanent dentition who present with specific types of malocclusion. Eligible participants must have Class 1 malocclusion with spacing and crowding within the range of 2-3 mm, as well as those with Class 2 Division 1 malocclusion. This selection ensures a uniform group for evaluating the effects of gold nanoparticle-coated thermoplastic orthodontic retainers on oral and gingival health.
Exclusion criteria
Exclusion criteria: Physically challenged patients. Cleft lip and Palate. Mentally challenged.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The study will evaluate gold nanoparticle-coated retainers for their effects on oral and gingival health and antimicrobial properties. We expect reductions in Porphyromonas gingivalis and Streptococcus mutans, improved gingival health, and positive feedback at 15 and 30 days. Comparative and statistical analyses will assess effectiveness and guide future research.Timepoint: The time points for this study are: Baseline (at retainer delivery) 15 days post-delivery 30 days post-delivery | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary outcomes of the study will focus on patient experience and overall health, including comfort and satisfaction with the retainers, any changes in taste perception, and sensory feedback. Patient compliance and ease of use will be monitored, along with any adverse reactions such as allergies or irritation. The aesthetic appeal and its impact on patient confidence will be assessed. Additionally, the study will evaluate the longevity and durability of the gold nanoparticle-coated retainers. These outcomes will provide insights into the practicality, patient acceptance, and overall effectiveness of the retainers in real-world use.Timepoint: The secondary outcomes of the study will be assessed at multiple time points to gauge patient experience and overall health. Evaluations will be conducted at baseline, 15 days, and 30 days after retainer delivery. These assessments will include patient comfort and satisfaction, changes in taste perception, sensory feedback, compliance, ease of use, any adverse reactions, aesthetic appeal, and the longevity and durability of the retainers. | — |
Countries
India
Contacts
Public ContactDr Shreya Chinnawar
Krishna Vishwa Vidyapeeth
Outcome results
None listed