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A comparative trial of injectable acyclovir versus injectable bleomycin in palmoplantar warts

INJECTABLE ACYCLOVIR VERSUS INJECTABLE BLEOMYCIN IN THE TREATMENT OF PALMOPLANTAR WARTS: A SPLIT PALMOPLANTAR COMPARATIVE TRIAL - nil

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/08/072406
Enrollment
120
Registered
2024-08-12
Start date
Unknown
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B070- Plantar wart

Interventions

Intervention1: INJECTABLE ACYCLOVIR: • a modified intralesional acyclovir therapy will be used. • A solution will be made by diluting 250mg of acyclovir in 4ml of distilled water and 1 ml of lignocai

Sponsors

NIL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with less than 10 warts in each arm with recalcitrant palmoplantar or periungual presentation. ( Recalcitrant warts are defined as warts previously treated via multiple modalities with no effect for more than 6 months ) All patients between the age of 18-64 years of age Patients with warts on both sides of the palms or soles

Exclusion criteria

Exclusion criteria: Patients who were under any topical or systemic treatment of warts in the last 4 weeks Pregnant or lactating women Immunocompromised patients Patients on any immunosuppressive medications Active or past history of tuberculosis Keloidal tendency Patients with history of hypersensitivity to Acyclovir or Bleomycin

Design outcomes

Primary

MeasureTime frame
Response to treatment(Complete response is a hundred percent resolution of warts with the return of dermatoglyphics. Partial response is more than fifty percent resolution with altered dermatoglyphics. No response is less than fifty percent resolution of warts.)Timepoint: 2nd week , 4th week , 6th week , 8th week and 10th week

Secondary

MeasureTime frame
number of warts.( Number of warts undergoing complete resolution)Timepoint: 2nd week, 4th week , 6th week , 8th week & 10th week.

Countries

India

Contacts

Public ContactAkash Agarwal

Department of dermatology, IMS and SUM hospital, bhubaneswar

maitreyeepanda@soa.ac.in9437218952

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026