To Assess The Effect Of Preoperative Transcranial Magnetic Stimulation On Post Surgical Pain After Breast Surgery

To Assess The Effect Of Preoperative Repititive Transcranial Magnetic Stimulation On Post Mastectomy Pain Syndrome: A Randomised Control Trial - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/08/072404

Enrollment

Registered

2024-08-12

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C50-C50- Malignant neoplasms of breast

Interventions

Intervention1: Intervention group - Repetitive transcranial magnetic stimulation (rTMS): Repetitive transcranial magnetic stimulation (rTMS) is non-invasive brain stimulation. Patients will receive

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age 18-70 years, 2. American Society of Anaesthesiologists (ASA) physical status I-III, 3. Scheduled for elective surgery for breast cancer (unilateral surgical procedure with or without axillary lymph node dissection).

Exclusion criteria

Exclusion criteria: 1. Patient refusal, 2. Contraindications to transcranial magnetic stimulation: iii. Patients who have ferromagnetic or magnetic sensitive metal objects implanted in the head or neck areas in close proximity to the TMS coil magnetic fields. iv. Surgical placement of medical devices (eg, metal plates, clips, electrodes, chips, pumps, stimulators, cochlear implants, pacemakers), as well as past exposure to all metal fragments, tattoos rendered with ferromagnetic-containing ink, permanent piercings, and/or other possible metal sources in the head and neck. 3. Neurological or psychiatric disorders, concurrent major depression,H/o head trauma 4. History of substance abuse, 5. ASA-PS IV or more, 6. History of Head trauma.

Design outcomes

Primary

Measure	Time frame
To assess the reduction in incidence of PMPS using SF-MPQ and EQ-5D-3L questionnaire.Timepoint: at 3 months	—

Secondary

Measure	Time frame
Secondary outcomes include assessment of postoperative opioid consumption up to 24 hrs and postoperative pain assessment up to 24 hours using Numeric Pain Rating Scale (NRS).Timepoint: up to 24 hours in post-operative period	—

Countries

India

Contacts

Public ContactDR Nishkarsh Gupta

ALL INDIA INSTITUTE OF MEDICAL SCIENCES NEW DELHI

drnishkarsh@rediffmail.com9013310014

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026