Effect of using enzyme which boost the activity of minoxidil in the treatment of Male baldness

Comparing the efficacy of topical application of 5 percent MINOXIDIL ALONE vs topical SULFOTRANSFERASE (SULT1A1) enzyme booster followed by 5 percent MINOXIDIL in the treatment of androgenetic alopecia- A non blinded randomized control study among patients attending dermatology and cosmetology opd - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/08/072403

Enrollment

Registered

2024-08-12

Start date

Unknown

Completion date

Unknown

Last updated

2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L649- Androgenic alopecia, unspecified

Interventions

Intervention1: Topical sulfotransferase(SULT1A1) enzyme booster followed by topical 5% minoxidil: Male patients with androgenetic alopecia are advised to apply 1 ml of topical sulfotransferase(SULT1A1

Eligibility

Inclusion criteria

Inclusion criteria: Male patients having Androgenetic alopecia grade 2 to 5(Norwood Hamilton scale) Age between 18 years and 45 years Patients willing for the study, consent and follow up Patients not on any other treatment for androgenetic alopecia for past 6 months

Exclusion criteria

Exclusion criteria: Patients below 18 years and above 45 years. Female patients having androgenetic alopecia. Concomitant dermatological disorders on the scalp other than androgenetic alopecia, serious cardiovascular disease, hepatic diseases, renal diseases. History of treatment with systemic or locally acting medication which may interfere with the study objectives, such as minoxidil, finasteride treatment in the past 6 months or treatment with other hair growth products in the past 6months Patients with unrealistic expectation.

Design outcomes

Primary

Measure	Time frame
assessed by measuring hair density, hair diameter, hair count per follicular unit, interfollicular distance, serial photographic assessmentTimepoint: every month for 6 months	—

Secondary

Measure	Time frame
subjective satisfaction will be assessed by patients self assessment through the following set of questionnaries.Timepoint: after 6 months	—

Countries

India

Contacts

Public ContactDr Saravanan N

The Tamilnadu Dr. M.G.R. medical university, chennai

saransudar@gmail.com9444500333

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026