The main outcome of this study is to study the effects of adding Dexmedetomidine to 4 percent Lignocaine nebulization on hemodynamics parameters in participants undergoing endotracheal intubation posted for surgeries under general anaesthesia

Effects of adding Dexmedetomidine to 4 Percent Lignocaine nebulization on hemodynamic stress response to laryngoscopy and intubation : A Randomized Control Trial - nil

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/08/072395

Enrollment

Registered

2024-08-12

Start date

Unknown

Completion date

Unknown

Last updated

2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: 4% Lignocaine plus Dexmedetomidine nebulization: Group DL : Patients will be nebulized with 4.5 ml 4% Lignocaine plus Dexmedetomidine 1µ/ kg body weight in 0.5ml saline Intervention2: 4

Eligibility

Inclusion criteria

Inclusion criteria: either gender of age 18-40 ears and ASA I and ASA II status patients posted for elective surgeries requiring endotracheal intubation under general anaesthesia.

Exclusion criteria

Exclusion criteria: Patients with increased risk of regurgitation and aspiration of gastric Contents. Patients with Difficult airway. Patients with upper respiratory tract infections Patients with hepatic or renal insufficiency Patients with history of smoking or exposure to household smoke. Patients with Cardiac diseases Pregnant patients Patients with known allergy to study drug

Design outcomes

Primary

Measure	Time frame
To evaluate the effects on the Heart rate and Blood pressure (SBP, DBP and MAP) in adult patients. Timepoint: 5 minutes before nebulization, immediately intubation, 1minute after intubation,5 minutes after intubation, 30 minutes after extubation	—

Secondary

Measure	Time frame
To evaluate the postoperative sore throat & pain.Timepoint: Before nebulization, after intubation, after extubation	—

Countries

India

Contacts

Public ContactLata Devi

Maharishi Markendeshwar institute of medical sciences and research , Mullana

lkanand11@gmail.com9463963930

Outcome results