Conservative strategy for preventing nausea and vomiting after surgery in low-risk patients

Efficacy of a restrictive anti-emetic strategy in patients with low risk of postoperative nausea and vomiting (PONV)- A randomised control trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/08/072352

Enrollment

640

Registered

2024-08-12

Start date

Unknown

Completion date

Unknown

Last updated

2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: ondansetron 4mg IV: ondansetron 4mg IV Control Intervention1: Inj ondansetron and Inj Dexamethasone: Inj ondansetron 4mg IV and Inj Dexamethasone 8 mg IV is compared with Inj ondans

Eligibility

Inclusion criteria

Inclusion criteria: 1. patients with APFEL score 2or less preoperatively 2. duration of surgery less than 60 minutes 3. surgeries under spinal/regional/ local anaesthesia

Exclusion criteria

Exclusion criteria: surgeries with high risk of PONV like middle ear surgeries, laparotomy

Design outcomes

Primary

Measure	Time frame
Incidence of PONV in both groups in first 24 hours after surgery.Timepoint: 1) patients will be monitored for 24 hrs after surgery . 2)duration of study is 1 year	—

Secondary

Measure	Time frame
Need for rescue antiemetics in 24 hoursTimepoint: 1) patients will be monitored for 24 hrs after surgery . 2)duration of study is 1 year	—

Countries

India

Contacts

Public ContactDR CHAITRA V

Dr Chandramma Dayanand Sagar Institute of Medical Science & Research

chaitra1591@gmail.com9113518096

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026