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In this study 2 drugs are used to compare their effects on patients vitals during the surgery, the amount of anaesthesia drugs needed and how is the pain after the surgery in patients undergoing elective thoracic and lumbar spine surgeries.

Effect of low dose ketamine with dexmedetomidine vs fentanyl on anesthetic requirements, intraoperative hemodynamics and recovery profile in patients undergoing elective thoracic and lumbar spine surgeries. - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/08/072344
Enrollment
30
Registered
2024-08-12
Start date
Unknown
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M959- Acquired deformity of musculoskeletal system, unspecified Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: Ketamine,dexmeditomidine: The drugs are given IV infusion at dose of 0.25 mg/kg/hr of ketamine and 0.25mcg/kg/hr of dexmedetomidine throughout the surgery from induction untill skin clo

Sponsors

Jagarapu kusuma
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age group 18 to 70 years ASA status 1 or 2 Patients undergoing elective thoracic/ lumbar spine surgery under general anaesthesia.

Exclusion criteria

Exclusion criteria: Age group below 17 and above 70 years 2.ASA status III and above 3. Pregnancy 4. Patients for emergency surgical procedures 5. Patients with uncontrolled hypertension or uncontrolled Diabetes mellitus 6. Patients with cardiac dysfunction such as ischemic heart disease, heart blocks, valvular disease and heart failure 7 Patients with severe respiratory disease such as asthma or chronic obstructive pulmonary disease. 8. Patients with severe hepatic, renal or endocrine disease 9. Patients who have undergone prior spine surgeries 10. Patients with history of drug abuse

Design outcomes

Primary

MeasureTime frame
To access the effect of low dose Ketodex infusion on intraoperative analgesic and anaesthetic requirements(amount of anesthetic and analgesics used)Timepoint: Intra operative , post induction to extubation.—

Secondary

MeasureTime frame
To access the effect of low dose Ketodex infusion on intraoperative hemodynamic profile, blood loss during the surgery and emergence from anaesthesia.Timepoint: Intra operative , post induction to extubation.—

Countries

India

Contacts

Public ContactDr Archana K Raichurkar

Manipal hospital

archana.raichurkar@gmail.com9980362958

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026