Health Condition 1: G55- Nerve root and plexus compressionsin diseases classified elsewhere
Conditions
Interventions
Intervention1: Ketofol (Ketamine + Propofol): A single intravenous bolus dose of Propofol 1.5mg per kg + Ketamine 0.75 mg/kg diluted to 20ml with normal saline to be given and observed over 30 minutes
Sponsors
NIL
Eligibility
Inclusion criteria
Inclusion criteria: Age 18-65years American society of Anesthesiologists physical status grade (ASA-PS) I and II Patients requiring GA with endotracheal intubation Patients willing to give the written consent to participate in the study
Exclusion criteria
Exclusion criteria: Patients who are not willing to participate in the study. Patients with uncontrolled hypertension & diabetes mellitus Patients with history of psychiatric illness Patients with history of intolerance or showing anaphylactic reaction to the medications used in the study. Patients with hepatic, renal, cardiac and seizure disorders Pregnant and lactating women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the Hemodynamic profile (Heart Rate, Systolic Blood Pressure, Diastolic Blood Pressure, and Mean Arterial Pressure) before induction, 1min after induction, 1 min, 3 min, and every 5 min after intubation for a duration of 30 min between the two study groups. Timepoint: 1 min, 3 min, and every 5 min after intubation for a duration of 30 min | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the recovery time, the need for postoperative rescue analgesia, the incidence of postoperative nausea and vomiting and the level of sedation between the two study groupsTimepoint: every 30mins | — |
Countries
India
Contacts
Public ContactDr Karthik E V N
Sri Venkateswara institute of medical sciences
Outcome results
None listed