Health Condition 1: H348- Other retinal vascular occlusions
Conditions
Interventions
Intervention1: AntiVEGF: Anti vascular endothelial growth
factor shall be injected
intravitreally in patients with branch retinal vein occlusion and optical
coherence tomography
angiography evaluation
Sponsors
Maulana Azad Medical College
Eligibility
Inclusion criteria
Inclusion criteria: 1. Treatment naïve patients in the age group of 45-65 years having branch retinal vein occlusion of less than three months duration along with macular edema(Central foveal thickness of =300 micrometers) 2. Subjects having best corrected visual acuity of at least 6/60
Exclusion criteria
Exclusion criteria: 1. Patients having ocular conditions associated with accumulation of sub-retinal fluid or macular affection like diabetic retinopathy, polypoidal choroidal vasculopathy (PCV), ocular inflammations, age-related macular degeneration, pathologic myopia and angioid streaks 2. Patients who have undergone any intraocular surgery other than uncomplicated cataract extraction 3. Risk of thrombo-embolic events and/or occurrence of these within past 6 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in Optical coherence tomography angiography parameters (Foveal Avascular Zone & vessel density) at one month following ranibizumab biosimilar injectionTimepoint: 1 month | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in Best corrected visual acuity following ranibizumab biosimilar injectionTimepoint: 1 month;Changes in Posterior segment Optical Coherence Tomography parameters (Central foveal thickness & sub-foveal choroidal thickness) following ranibizumab biosimilar injectionTimepoint: 1 month; Serum levels of vascular endothelial growth factors in subjects of branch retinal vein occlusionTimepoint: 1 month | — |
Countries
India
Contacts
Public ContactDr Apoorva Goyal
Maulana Azad Medical College
Outcome results
None listed